Symbol Name ID |
Cntf
ciliary neurotrophic factor MGI:88439 |
* | Aspects of the system are reported to show a normal phenotype. |
Darker colors indicate more annotations |
Human Phenotypes | Gliosis |
Cerebellar atrophy |
Neuronal loss in central nervous system |
Gait ataxia |
Bradykinesia |
Chorea |
Depression |
Personality changes |
Dementia |
Hyperreflexia |
Seizure |
Disease(s) Associated with CNTF | |||||||||||
Huntington's disease |
Mouse Phenotypes | nervous system phenotype |
decreased oligodendrocyte progenitor number |
abnormal oligodendrocyte apoptosis |
abnormal axon extension |
abnormal neuron proliferation |
abnormal microglial cell morphology |
increased cerebral infarct size |
astrocytosis |
abnormal motor neuron morphology |
decreased motor neuron number |
motor neuron degeneration |
abnormal myelin sheath morphology |
decreased neuronal precursor cell number |
axon degeneration |
abnormal astrocyte physiology |
|
Availability | Mouse Genotype | |||||||||||||||
Cntftm1Gdy/Cntftm1Gdy | * | |||||||||||||||
Cntftm1Mpin/Cntftm1Mpin | * | |||||||||||||||
Cntftm1Vlcg/Cntftm1Vlcg | * |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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